Unofficial Open Targets MCP Server 🧬
About
Unofficial Model Context Protocol server for accessing Open Targets platform data for gene-drug-disease associations research.
Explore
All 6 tools working with live Open Targets API data:
- 🎯 Target Search - Gene symbols, names, descriptions (BRCA1, TP53, etc.)
- 🦠Disease Search - Names, synonyms, descriptions (cancer, diabetes, etc.)
- 🔗 Target-Disease Associations - Evidence scores from 20+ databases
- 📊 Disease Target Summaries - Prioritized therapeutic targets
- 🧬 Target Details - Comprehensive gene/protein information
- 🎠Disease Details - Complete disease profiles with ontologies
Setting up with Highlight
This MCP is not yet compatible with Highlight’s one-click setup. However, you can still use it with Highlight by following these steps:
- Download and install Highlight from highlightai.com/download
- Navigate to the plugins tab and select "Add Custom Plugin"
-
Configure the plugin with the settings below
Plugin Name
Unofficial Open Targets MCP Server 🧬Command (node, npx, python, etc.)Please refer to the README for specific instructions on how to obtain API keys or other required environment variables.
- Enable "Start Automatically" if you want the plugin to start when Highlight launches
From the repository
Install and build the server with npm install and npm run build, then run it with node build/index.js. Configure it as an MCP client (e.g., Claude Desktop) by adding the server to the mcpServers object with the node command and path to the built index.js.
Claude Desktop / Cursor
Paste into your MCP client config file to install this server.
{
"mcpServers": {
"unofficial open targets mcp server \ud83e\uddec": {
"Augmented-Nature-OpenTargets-MCP-Server": {
"command": "node",
"args": [
"build/index.js"
]
}
}
}
}McpServers
{
"Augmented-Nature-OpenTargets-MCP-Server": {
"command": "node",
"args": [
"build/index.js"
]
}
}Unofficial Model Context Protocol server for accessing Open Targets platform data for gene-drug-disease associations research.
Developed by Augmented Nature
✅ Verified Features
All 6 tools working with live Open Targets API data:
- 🎯 Target Search - Gene symbols, names, descriptions (BRCA1, TP53, etc.)
- 🦠Disease Search - Names, synonyms, descriptions (cancer, diabetes, etc.)
- 🔗 Target-Disease Associations - Evidence scores from 20+ databases
- 📊 Disease Target Summaries - Prioritized therapeutic targets
- 🧬 Target Details - Comprehensive gene/protein information
- 🎠Disease Details - Complete disease profiles with ontologies
🚀 Quick Start
```bash
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