OFFX MCP Server

- Direct access to OFFX (Target Safety) drug and safety database
- Search by drug, adverse event, target, action, or name
- Retrieve alerts and scores for drugs
- Structured JSON responses
- Pagination support for large result sets

1. search_drugs
- Search drugs by name
- Input: { drug: string }
- Example: { "drug": "everolimus" }

2. get_drugs
- Get drugs by either both target_id and action_id (together), or only adverse_event_id (not just one of target_id/action_id)
- Input: { target_id?: string, action_id?: string, adverse_event_id?: string, page?: number }
- You must provide:
- both target_id and action_id (for target/class search), or
- only adverse_event_id (for adverse event search)
- page defaults to 1 if not specified
- Examples:
- { "target_id": "123", "action_id": "456" }
- { "adverse_event_id": "10001551" }

3. get_alerts
- Get alerts for a drug (by drug_id) or a target (by target_id, with optional action_id)
- Input: { drug_id?: string, target_id?: string, action_id?: string, page?: number, adverse_event_id?: string, ref_source_type?: string, alert_type?: string, alert_phase?: string, alert_level_evidence?: string, alert_onoff_target?: string, alert_severity?: string, alert_causality?: string, alert_species?: string, alert_date_from?: string, alert_date_to?: string, order_by_date?: string, order_by_adv?: string }
- Requirements:
- You must provide exactly one of: drug_id or target_id (not both, not neither)
- For drug alerts: drug_id is required
- For target alerts: target_id is required, action_id is optional
- page is required but defaults to 1 if not specified
- Examples:
- { "drug_id": "11204", "page": 1 }
- { "target_id": "158", "page": 1 }
- { "target_id": "158", "action_id": "15", "page": 2, "alert_type": "2" }

4. get_score
- Get drug score by drug_id (and optionally adverse_event_id), or get target/class score by target_id and action_id (and optionally adverse_event_id)
- Input: { drug_id?: string, adverse_event_id?: string, target_id?: string, action_id?: string }
- Requirements:
- You must provide either drug_id (alone), or both target_id and action_id (together)
- Do not provide neither, all, or just one of target_id/action_id
- Examples:
- { "drug_id": "99402" }
- { "drug_id": "99402", "adverse_event_id": "10001551" }
- { "target_id": "158", "action_id": "15" }
- { "target_id": "158", "action_id": "15", "page": 2, "alert_type": "2" }

5. get_drug
- Get drug masterview by drug id (with optional filters)
- Input: { drug_id: string, page: number, adverse_event_id?: string, ref_source_type?: string, alert_type?: string, alert_phase?: string, alert_level_evidence?: string, alert_severity?: string, alert_causality?: string, alert_species?: string, alert_date_from?: string, alert_date_to?: string }
- Examples:
- { "drug_id": "11204", "page": 1 }
- { "drug_id": "11204", "page": 2, "alert_type": "2" }

6. search_adverse_events
- Search adverse events by name (min 3 chars)
- Input: { adverse_event: string }
- Example: { "adverse_event": "Anaemia" }

7. get_adverse_events
- Get adverse events by drug id or target id (provide exactly one)
- Input: { drug_id?: string, target_id?: string }
- Examples:
- { "drug_id": "12345" }
- { "target_id": "67890" }

8. search_targets
- Search targets by target name
- Input: { target: string }
- Example: { "target": "ALK" }

9. get_target
- Get target masterview by target_id and action_id (both required; with optional filters)
- Input: { target_id: string, action_id: string, page?: number, adverse_event_id?: string, ref_source_type?: string, alert_type?: string, alert_phase?: string, alert_level_evidence?: string, alert_onoff_target?: string, alert_severity?: string, alert_causality?: string, alert_species?: string, alert_date_from?: string, alert_date_to?: string }
- Requirements:
- Both target_id and action_id are required
- page is optional and defaults to 1 if not specified
- Examples:
- { "target_id": "158", "action_id": "15" }
- { "target_id": "158", "action_id": "15", "page": 2, "alert_type": "2" }

10. get_targets
- Get primary or secondary targets for a drug by drug_id, or targets by adverse_event_id
- Input: { drug_id?: string, type?: 'primary' | 'secondary', adverse_event_id?: string }
- Requirements:
- You must provide exactly one of: drug_id or adverse_event_id (not both, not neither)
- If drug_id is provided and type is not specified, it defaults to 'primary'
- Returns:
- { primary_targets: [...] } or { secondary_targets: [...] } (for drug search)
- { targets: [...] } (for adverse event search)
- Examples:
- { "drug_id": "11204" } (returns primary targets)
- { "drug_id": "11204", "type": "secondary" }
- { "adverse_event_id": "10001551" }

> Note: See the Supported Formats and Optional Filter Parameters sections above for allowed values and formats for filter fields such as adverse_event_id, alert_type, alert_phase, ref_source_type, alert_level_evidence, alert_onoff_target, alert_severity, and ordering fields.