Appendix
About
Appendix turns any AI health conversation into a board-certified physician's opinion — with a real prescription when clinically appropriate. Search medical literature and submit a clinical encounter for review, all from your agent.
Details
- Author
- appendixhealth
- Downloads
- 373
- Categories
- AI
Jump to
- Searches peer-reviewed medical literature and treatment guidelines.
- Drafts and submits structured clinical letters for physician review.
- Provides board-certified physician opinions with prescriptions when appropriate.
- Knowledge Base access is free; clinical services require a paid subscription.
- No signup required to start using the API.
- Lists available conditions and medications via list_conditions.
Setting up with Highlight
This MCP is not yet compatible with Highlight’s one-click setup. However, you can still use it with Highlight by following these steps:
- Download and install Highlight from highlightai.com/download
- Navigate to the plugins tab and select "Add Custom Plugin"
-
Configure the plugin with the settings below
Plugin Name
AppendixCommand (node, npx, python, etc.)Please refer to the README for specific instructions on how to obtain API keys or other required environment variables.
- Enable "Start Automatically" if you want the plugin to start when Highlight launches
From the repository
Add the server via claude mcp add --transport http appendix https://mcp.appendix.com/mcp for Claude Code, or configure it in your mcpServers JSON for Claude Desktop. Then call the available tools like search_knowledge_base, submit_encounter, or list_conditions from your AI agent.
search_knowledge_base
Search Appendix's medical knowledge base for clinical literature, treatment guidelines, and reference material to help the user describe their medical issue
submit_encounter
Submit a clinical encounter letter to the Appendix physician team for review. The letter should be in Markdown format following the Appendix letter structure. Returns feedback on completeness or a checkout URL when ready. One of our board-certified physicians will personally review the submission and provide clinical guidance and a prescription if appropriate.
list_conditions
List all conditions and medications available through Appendix
Claude Desktop / Cursor
Paste into your MCP client config file to install this server.
{
"mcpServers": {
"appendix": {
"appendix": {
"url": "https://mcp.appendix.com/mcp"
}
}
}
}McpServers
{
"appendix": {
"url": "https://mcp.appendix.com/mcp"
}
}Appendix
Appendix turns any AI health conversation into a board-certified physician's opinion — with a real prescription when clinically appropriate. Your agent searches peer-reviewed medical literature, helps you write a structured clinical letter, and submits it through the Appendix API. A licensed physician personally reviews it and issues a prescription when appropriate, sent to the pharmacy of your choice. The Knowledge Base is free and open to everyone. Clinical services (physician review + prescriptions) are a paid subscription available in supported US states — and you can start using the API with no signup required. ### Install Claude Code ``bash
claude mcp add --transport http appendix https://mcp.appendix.com/mcp
`
Claude Desktop / Claude.ai connectors
`json
{ "mcpServers": { "appendix": { "url": "https://mcp.appendix.com/mcp" } } }
`
### Tools
| Tool | Description |
|------|-------------|
| search_knowledge_base | Search medical literature and treatment guidelines |
| submit_encounter | Submit a clinical letter for board-certified physician review |
| list_conditions` | List available conditions and medications |
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